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. 2019 May 7;9:311. doi: 10.3389/fonc.2019.00311

Table 1B.

Reproductive and hormonal characteristics of women by case status.

Cases (n = 267) Controls (n = 226) p-valuea
Mean ± SD
Menstrual duration b (years) 31.2 ± 5.2 32.2 ± 5.1 0.09
Age at menopause b (years) 46.3 ± 5.0 46.9 ± 4.8 0.3
Age at menarche (years) 14.9 ± 1.7 14.7 ± 1.6 0.3
Number of pregnancies (gravidity) 5.1 ± 2.6 4.4 ± 2.4 0.003
Age at first birth c (years) 20.0 ± 3.5 19.8 ± 3.3 0.42
Age at first live birth c (years) 20.1 ± 3.6 19.8 ± 3.4 0.38
N %d N %d p-valuea
Still menstruating (yes) 25 9.4 71 31.4 <0.0001
Age at menarche (years) 0.17
  <14 46 17.2 50 22.1
 14 58 21.7 62 27.4
 ≥15 134 50.2 101 44.7
Age at menopause (years) <0.0001
 Premenopausal 25 9.4 71 31.4
  <45 61 22.9 39 17.3
 45–49 98 36.7 55 24.3
 ≥50 71 26.6 52 23.0
Number of pregnancies (gravidity) 0.005
  ≤ 2 40 15.0 43 19.0
 3–5 116 43.5 121 53.5
 >5 111 41.6 62 27.4
Age at first birth (years) 0.8
 Never Pregnant 15 5.6 10 4.4
  <18 50 18.7 47 20.8
 18–20 100 37.5 80 35.4
 ≥21 77 28.8 69 30.5
Age at first live-birth (years) 0.9
 Never Pregnant 15 5.6 10 4.4
  <18 50 18.7 47 20.8
 18–20 98 36.7 80 35.4
 ≥21 79 29.6 69 30.5
Birth control use (ever) 29 10.9 39 17.3 0.04

SD, standard deviation; N, number of participants.

a

P-values generated by t-test or chi-square test; unknown category or missings excluded.

b

Only among postmenopausal women.

c

Only among women who reported being pregnant.

d

Percentages may not add up to 100 because of rounding and due to unknown categories (not shown).