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. 2019 May 7;9:311. doi: 10.3389/fonc.2019.00311

Table 3.

Mutually adjusted odds ratios and 95% confidence intervals of reproductive and hormonal factors in relation to lung cancer in the hospital-based lung cancer case-control study.

Cases Controls Mutually adjusted a
N N OR (95% CI)
Age at menarche (years)
  <14 46 50 1.04 (0.57, 1.87)
 14 58 62 0.84 (0.48, 1.46)
 ≥15 134 101 1 (referent)
Age at menopause (years)
 Premenopausal 25 71 0.71 (0.29, 1.70)
  <45 61 39 1.74 (0.90, 3.38)
 45–49 98 55 1.72 (0.94, 3.15)
 ≥50 71 52 1 (referent)
Number of pregnancies (gravidity)
  ≤ 2 40 43 0.82 (0.40, 1.68)
 3–5 116 121 1 (referent)
 >5 111 62 1.15 (0.69, 1.91)
Age at first live-birth (years)
 Never Pregnant 15 10 2.39 (0.55, 10.36)
  <18 50 47 0.75 (0.40, 1.41)
 18–20 98 80 1 (referent)
 ≥21 79 69 0.77 (0.45, 1.31)
Birth control use
 Ever 29 39 0.82 (0.42, 1.59)
 Never 227 177 1 (referent)

OR, odds ratio; CI, confidence interval.

a

Estimates were simultaneously adjusted for all reproductive and hormonal exposures listed above, in addition to adjustment for age and cumulative active smoking years; one subject with missing cumulative active smoking history was excluded.

Unknown categories were retained in the model but not presented here.