FIGURE 5.

Effect of PJ34 and cisplatin or temozolomide on ratio of short per long OPA1 isoforms in B16F10 cells. Panel (A₁,B₁,C₁) shows representative immunoblots of PAR and OPA1 from cells treated as indicated in the figure. S-OPA1 and L-OPA1 indicate its short and long isoforms, respectively. β-Actin was used for loading control. Panel (A₂,B₂,C₂) display densitometry results of corresponding immunoblots. Values are expressed as mean + SEM, N = 3, ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001; NS, non-significant.