Figure 8.

Role of PKA in the synergism of cAMP and Ca²⁺ signalling for duodenal epithelial anion secretion. (a–b) Representative time courses and summary data showing the synergistic effect of low dose forskolin (For) addition followed by low dose caffeine (Caf) in the absence or the presence of H‐89 (20 μM, n = 6). (c–d) Representative time courses and summary data showing the synergistic effect of low dose forskolin addition followed by low dose carbachol (CCh) in the absence or the presence of H‐89 (20 μM, n = 6). ns: no significant differences, ^* P < 0.05, significantly different from those without H‐89