Skip to main content
. 2019 Apr 15;176(11):1664–1679. doi: 10.1111/bph.14615

Figure 4.

Figure 4

Exogenous RANKL exaggerates Th2 immune responses in AR mice. We sensitized mice on Days 1, 5, and 14 by i.p. injections of 100 μg of OVA emulsified in 20 mg of aluminium hydroxide and challenged mice with 1.5 mg of OVA or recombinant mouse RANKL for 10 days. (a) The number of nose rubs that occurred 10 min after OVA or RANKL intranasal provocation. (b) IgE levels in the serum were measured by elisa. (c) The levels of histamine in serum were measured by a histamine assay method. (d–l) The levels of cytokines in the serum were measured by elisa. Data shown are the means ± SEM from n = 5 mice per group. # P < 0.05; significantly different from OVA‐unsensitized mice (PBS)