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. 2019 Apr 22;176(11):1745–1763. doi: 10.1111/bph.14648

Figure 1.

Figure 1

Expression pattern of key components of the protein phosphatase system in primary human aortic endothelial (HAEC), aortic smooth muscle (HASMC), cardiac fibroblast (HCF‐av) cell lines, and AC16 ventricular cardiomyocytes: catalytic subunit expression (a, b), scaffolding subunit expression (c), regulatory subunit expression (d, e), and endogenous regulators (f). The mRNA expression profile was determined using semi‐quantitative RT‐PCR‐based SYBR green chemistry. Data are presented relative to the expression level in HAEC (mean ± SEM) and were analysed using one‐way ANOVA with post hoc analysis (Bonferroni). *P < 0.05 (n = 6). CIP2A, gene coding cancerous inhibitor of PP2A; LCMT‐1, gene coding leucine carboxyl methyltransferase 1; PPP1CA, gene coding protein phosphatase 1 catalytic subunit A; PPP2CA, gene coding protein phosphatase 2A catalytic subunit A; PPP4C, gene coding protein phosphatase 4 catalytic subunit; PPP2R1A/1B, genes coding PP2A scaffolding subunit Aα/β; PP2R2A/3A/3B/4/5A/5D, genes coding PP2A regulatory subunits; PTEN, gene coding phosphatase and tensin homologue