Table 1.
Biodistribution of 211At-MABG in ICR Mice
| (% ID/g) | 1.5 Minutes | 1 Hour | 3 Hours | 24 Hours |
|---|---|---|---|---|
| Blood | 16.9 ± 2.5 | 2.3 ± 0.3 | 2.0 ± 0.4 | 0.5 ± 0.1 |
| Brain | 1.3 ± 0.2 | 0.3 ± 0.0 | 0.2 ± 0.0 | 0.1 ± 0.0 |
| Heart | 26.8 ± 4.5 | 11.5 ± 1.5 | 9.3 ± 1.1 | 2.0 ± 0.4 |
| Lung | 37.5 ± 6.4 | 10.2 ± 2.0 | 7.3 ± 0.1 | 1.9 ± 0.5 |
| Liver | 5.8 ± 1.2 | 7.2 ± 0.7 | 4.8 ± 1.0 | 0.8 ± 0.1 |
| Spleen | 2.8 ± 1.2 | 7.5 ± 0.6 | 6.4 ± 0.6 | 2.0 ± 0.5 |
| Pancreas | 7.1 ± 1.6 | 4.5 ± 0.5 | 3.1 ± 0.3 | 0.7 ± 0.0 |
| Stomach | 3.4 ± 1.2 | 12.9 ± 3.3 | 12.8 ± 2.8 | 4.5 ± 1.3 |
| Intestine | 5.0 ± 1.6 | 6.4 ± 0.9 | 5.5 ± 0.5 | 1.4 ± 0.3 |
| Kidney | 19.6 ± 7.6 | 5.6 ± 2.0 | 3.5 ± 0.5 | 1.1 ± 0.2 |
| Adrenal gland | 18.0 ± 2.9 | 10.2 ± 0.7 | 10.0 ± 2.5 | 10.8 ± 5.2 |
| Muscle | 3.7 ± 0.5 | 1.8 ± 0.1 | 1.5 ± 0.3 | 0.4 ± 0.0 |
| Bone | 3.6 ± 0.2 | 2.4 ± 0.2 | 2.0 ± 0.3 | 0.5 ± 0.2 |
| (% ID) | 1.5 Minutes | 1 Hour | 3 Hours | 24 Hours |
| Thyroid | 0.3 ± 0.1 | 0.4 ± 0.1 | 0.5 ± 0.1 | 0.3 ± 0.1 |
Data are expressed as the percentage of injected radioactivity dose per gram (% ID/g), except the thyroid, which is expressed as injected radioactivity dose (% ID). Data are expressed as the mean ± standard deviation.