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. 2019 May 3;23:101852. doi: 10.1016/j.nicl.2019.101852

Table 2.

Results of partial least squares regression (PLSR) models with Trail Making Test A & B as the outcome variables. Age, education, and depression severity (Hamilton Depression Rating Scale [HDRS]) were entered into the models as covariates.

Model Number of PLSR Components Adjusted R2 PLSR Component Variables (Beta weights [association with outcome] in parentheses)
Trail Making Test A 1 0.07 Component 1: Left paracentral lobule (β = 0.06), left supramarginal gyrus (β = 0.60), left thalamus (β = 0.18), left pallidum (β = 0.24).
Trail Making Test B 2 0.35 Component 1: Left paracentral lobule (β = 0.12), left supramarginal gyrus (β = 0.34), left precentral gyrus (β = 0.03), left postcentral gyrus (β = 0.15), left thalamus (β = 0.23), left pallidum (β = 0.26), age (β = 0.21)
0.17
Component 2: Years of education (β = 0.44), depression severity (HDRS; β = 0.27)
Trail Making Test B/A Ratio 1 0.13 Component 1: right paracentral lobule (β = 0.12), left paracentral lobule (β = 0.36), left precentral cortex (β = 0.31), left postcentral cortex (β = 0.43), right posterior cingulate (β = 0.22), left caudal anterior cingulate (β = 0.23), left caudal middle frontal cortex (β = 0.32), right thalamus (β = 0.48), left putamen (β = 0.07), and left pallidum (β = 0.17)