Fig. 3.

Expression of genes involved in retrotransposon silencing and the Line-1 class of retrotransposons is diminished in teratoma-susceptible germ cells. (A-C) Oct4ΔPE::GFP-positive germ cells were FACS enriched from E13.5-E15.5 FVB, 129 and M19 gonads, and expression of (A) Tdrd1, (B) Tdrd9 and (C) Line-1 was analyzed by qPCR (n=4-8). Female germ cell expression data from all strains were pooled. Gene expression at all time-points was plotted relative to expression in E13.5 FVB male germ cells. Data are mean±s.e.m. *P<0.05; ^†P<0.01; ^‡P<0.001 and ^#P<0.0001.