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. 2019 Apr 19;20(8):1932. doi: 10.3390/ijms20081932

Table 2.

The associations between clinical tests and two potential biochemical markers.

Clinical Tests SS-DED Non-SS-DE
MMP-9 MMP-9/LF MMP-9 MMP-9/LF
OSDI score β −1.07 −0.30 0.29 0.15
ρ −0.39 −0.20 0.25 0.25
p value 0.27 0.58 0.49 0.49
NIKBUT first (s) β 8.64 −2.59 −5.56 −1.65
ρ 0.13 −0.09 −0.50 −0.66
p value 0.72 0.80 0.14 0.04 *
Central TMH (mm) β −945.3 −432.6 −368.0 −84.2
ρ −0.49 −0.20 −0.57 −0.42
p value 0.15 0.57 0.08 0.22
BN redness score β 84.7 46.7 13.7 21.9
ρ 0.56 0.73 0.16 0.47
p value 0.09 0.02 * 0.67 0.17
Mean redness score β 142.8 29.0 −13.2 12.7
ρ 0.95 0.59 0.16 0.18
p value 3 × 10−5 * 0.07 0.66 0.61

β is the slope of equation of simple liner regression between a clinical test and a biochemical marker. ρ is the Spearman’s correlation coefficient. p value < 0.05 was recognized as a statistically significant correlation (*) and p value < 0.1 was highlighted in bold. Abbreviation: SS, Sjögren syndrome. DED, dry eye disease. OSDI, ocular surface disease index. NIKBUT first, non-invasive keratographic first break-up time. TMH, tear meniscus height. BN, bulbar nasal.