DEL |
DNA-encoded library |
PDP |
Peptide Discovery Platform |
HTS |
high-throughput screening |
POI |
protein of interest |
NGS |
Next Generation Sequencing |
(q)PCR |
(quantitative) polymerase chain reaction |
SAR |
structure-activity relationship |
PDC |
peptide-drug conjugate |
LMW |
low molecular weight |
PPI |
protein-protein interaction |
DNA |
deoxyribonucleic acid |
(t)/ (m)/ (si)RNA |
(transfer)/ (messenger)/ (small interfering) ribonucleic acid |
ARS |
amino acyl tRNA synthetases |
MoA |
Mode of action |
MW |
molecular weight |
(k)Da |
(kilo)Dalton |
RaPID |
Random Peptide Integrated Discovery |
SICLOPPS |
Split-Intein Circular Ligation Of Peptides and Proteins |
PURE |
Protein synthesis Using Recombinant Elements |
IVT |
in vitro translation |
IC50 |
half maximal inhibitory concentration |
GPCR |
G protein-coupled receptor |
RIPK1 |
Receptor-interacting serine/threonine-protein kinase |
sEH |
soluble epoxide hydrolase |
EpCAM |
epithelial cell adhesion molecule |