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. 2019 Apr 25;24(8):1629. doi: 10.3390/molecules24081629
DEL DNA-encoded library
PDP Peptide Discovery Platform
HTS high-throughput screening
POI protein of interest
NGS Next Generation Sequencing
(q)PCR (quantitative) polymerase chain reaction
SAR structure-activity relationship
PDC peptide-drug conjugate
LMW low molecular weight
PPI protein-protein interaction
DNA deoxyribonucleic acid
(t)/ (m)/ (si)RNA (transfer)/ (messenger)/ (small interfering) ribonucleic acid
ARS amino acyl tRNA synthetases
MoA Mode of action
MW molecular weight
(k)Da (kilo)Dalton
RaPID Random Peptide Integrated Discovery
SICLOPPS Split-Intein Circular Ligation Of Peptides and Proteins
PURE Protein synthesis Using Recombinant Elements
IVT in vitro translation
IC50 half maximal inhibitory concentration
GPCR G protein-coupled receptor
RIPK1 Receptor-interacting serine/threonine-protein kinase
sEH soluble epoxide hydrolase
EpCAM epithelial cell adhesion molecule