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. 2019 Apr 19;24(8):1556. doi: 10.3390/molecules24081556

Figure 5.

Figure 5

Effects of phytosterols on the viability of ELT3 and primary human uterine leiomyoma (hUL) cells as well as human UtSMC cells. The chemical structure of (A) β-sitosterol and (B) stigmasterol. Treatment with β-sitosterol (0.25, 0.5, 1, and 2 μM) and stigmasterol (0.25, 0.5, 1, and 2 μM) for 48 h in (C,D) ELT3 cells as well as for 8 days in (E,F) hUL cells. Human normal UtSMC cells treated with (G) β-sitosterol and (H) stigmasterol at various concentrations (0.1 0.25, 0.5, 1, and 2 μM) for 48 and 96 h. At the end of incubation, the cell viability was detected using the MTT assay. Data represent means ± SEM (n = 6 in ELT3 and hUL cells; n = 4 in UtSMC cells). * p < 0.05, ** p < 0.01 compared with the control group.