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. 2019 Apr 23;20(8):1981. doi: 10.3390/ijms20081981

Figure 4.

Figure 4

Evolution of bRF-PH domain with known domain architectures and conserved gene neighborhoods. (A) Collapsed phylogenetic tree depicting the radiation of the bRF-PH domains. Key transitions are denoted in red lettering along the tree. (B–K) Notable domain architectures and conserved gene neighborhoods. See Figure 3 legend for further descriptions and details. Abbreviations: PSYN, pseudouridine synthase; RFR, RFH and RtcB-associating unknown domains; bac. codon recog., bacterial codon recognition domain.