Table 2.
The effects on kidney mass, Cd accumulation, and renal function related to urine parameters.
| Parameters | Group I | Group II | Group III | Group IV |
|---|---|---|---|---|
| Kidney mass (mg) | 47.24 ± 4.54 | 45.67 ± 3.92 | 55.67 ± 6.12 $ | 48.22 ± 5.01 * |
| Kidney mass/body mass (× 103) | 15.28 ± 1.48 | 13.94 ± 1.24 | 20.33 ± 2.17 # | 17.89 ± 1.31 * |
| Cd burden in kidney (ppm of wet tissue) | 0.02 ± 0.001 | 0.007 ± 0.0008 | 20.33 ± 2.37 # | 17.89 ± 1.31 * |
| Urinary creatinine (mg/dL) | 65.52 ± 6.33 | 64.33 ± 7.12 | 31.50 ± 3.21# | 41.57 ± 3.98 * |
| Urinary albumin (mg/dL) | 2.98 ± 0.24 | 2.78 ± 0.19 | 6.74 ± 0.75 # | 5.98 ± 0.49 * |
| Urinary nitrate/nitrite (nmol/g creatinine) | 0.85 ± 0.09 | 0.82 ± 0.08 | 1.45 ± 0.16 # | 1.17 ± 0.12 ** |
Data are represented as means ± SD (n = 6). $ Values significantly (p < 0.05) differ from normal control. # Values significantly (p < 0.01) differ from normal control. * Values significantly (p < 0.05) differ from toxic control. ** Values significantly (p < 0.01) differ from toxic control.