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. 2019 Mar 21;294(19):7787–7796. doi: 10.1074/jbc.RA118.006321

Figure 6.

Figure 6.

ELF4 modulates the expression of Pf4 and Ppbp during P. yoelii infection. A, quantification of bone marrow megakaryocytes was assessed by calculating the percentage of megakaryocytes in total bone marrow cells on the indicated days after infection. B, expression of Pf4 and Ppbp in isolated megakaryocytes from Elf4+/+ or Elf4−/− mice on day 0, 6, 9, or 18 after infection. C, protein level of Pf4 in peripheral platelets on day 0, 7, or 14 after P. yoelii infection from individual Elf4+/+ or Elf4−/− mice. D, protein level of Ppbp in peripheral platelets on day 0, 7, or 14 after P. yoelii infection from the same individual Elf4+/+ or Elf4−/− mice as in C. For B, gene expression was relative to Actb. For C and D, GAPDH was used as a control. The data in A and B are means ± S.D. (n = 3). All data are from two independent experiments; t test; *, p < 0.05; **, p < 0.01; NS, not significant.