ABC |
Adenosine Tri-Phosphate binding cassette |
AE2 |
apical Cl−/HCO3− anion exchanger 2 |
ASBT |
apical sodium bile acid co-transporter |
AKR1C4 |
3a-hydroxysteroid dehydrogenase |
AKR1D1 |
D4–3-oxosteroid-5b-reductase |
BAAT |
bile acid CoA-amino acid N-acyltransferase |
BACS |
bile acid CoA synthetase |
BDL |
bile duct ligated, (BSEP |
cAMP |
adenosine 3′,5′-cyclic monophosphate |
CCA |
cholangiocarcinoma |
CCl4
|
carbon tetrachloride |
CDCA |
chenodeoxycholic acid |
CYP27A1 |
Sterol 27-hydroxylase |
CFTR |
cystic fibrosis transmembrane conductance regulator |
CYP7B1 |
oxysterol 7a-hydroxylase |
CYP8B1 |
12a-hydroxylase |
cSrc |
Rous sarcoma oncogene |
DCA |
Deoxycholic Acid |
DHCA |
3a,7a-dihydroxy-5b-cholestanoic acid |
EGFR |
epidermal growth factor receptor |
ERK |
extracellular regulated protein kinase |
FXR |
Farnesoid receptor X |
HI |
hydrophobicity index |
HPLC |
high pressure liquid chromatography |
ICAM-1 |
intercellular adhesion molecule-1 |
IL6 |
interleukin-6 |
LCA |
Lithocholic Acid |
MAPK |
mitogen-activated protein kinase |
Mdr |
Multi-Drug Resistance |
MDR/TAP |
multi-drug-resistance/transporter associated with antigen processing |
NTCP |
sodium/taurocholate co-transporting polypeptide |
OST |
organic solute transporter |
PBP |
peri-biliary plexus |
PBC |
primary biliary cholangitis |
PCNA |
protein cellular nuclear antigen |
PI3K |
phosphatidylinositol 3-kinases |
PKA |
protein kinase A |
PKC |
protein kinase C |
PSC |
primary sclerosing cholangitis |
ROS |
reactive oxygen species |
SCT |
secretin |
S1PR2 |
Sphingosine 1-phosphate receptor 2 |
SR |
secretin receptor |
TCA |
Taurocholic acid |
TGR5 |
Transmembrane G protein coupled receptor |
THCA |
3 a,7a,12a-trihydroxy-5b-cholestanoic acid |
TLCA |
Taurolithocholic acid |
TUDCA |
Tauroursodeoxycholic acid |
UDCA |
Ursodeoxycholic acid |
VEGF |
vascular endothelial growth factor |
VLCS |
very long-chain acyl CoA synthetase |