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Orientation of the side chains observed at both non-cryogenic and cryogenic structures. The omit maps of side chain are presented at contour level 1.0 σ. The changes of sidechains located in (A) helix III-helix IV loop, (B) helix IV-helix V loop, (C) the end of beta sheet III and helix IV, (D) beta sheet IV and helix II, and (E) helix I and beta sheet III.
