ZIKV	Zika virus;
HCV	Hepatitis C Virus;
DENV	Dengue virus;
WNV	West Nile virus;
JEV	Japanese Encephalitis Virus;
DAA	direct-acting antiviral agents;
NSP	non-structural protein;
NS3	non-structural protein 3;
NS3PRO	non-structural protein 3 protease;
NS3HEL	non-structural protein 3 helicase;
ssRNA	single-stranded RNA;
NTP	nucleoside triphosphate;
PDB	Protein Data Bank;
NCI	National Cancer Institute;
SBDD	Structure-based drug discovery;
SAR	Structure-activity relationship;
SFXC	Surflex-Dock algorithm;