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. 2019 Apr 23;20(8):1988. doi: 10.3390/ijms20081988

Figure 7.

Figure 7

The Drosophila TPR is regulated by different mechanisms at different times of the day. Models for regulatory mechanisms of the TPR in each time range: daytime (ZT 1–12), night onset (ZT 10–15), and predawn (ZT 22–24). The daytime TPR: DN2s are the main clock neurons. DH31 acts on DH31R in a subset of clock neurons to regulate the daytime TPR. PDF is also involved in daytime TPR regulation. The night-onset TPR: DH31 acts on DN2s via PDFR to regulate the night-onset TPR. The predawn TPR: An AC-sLN-DN2 neural circuit regulates the proper setting of temperature preference before dawn.