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. 2019 Apr 12;20(8):1815. doi: 10.3390/ijms20081815

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The p-S727 PTM drives the STAT3 non-canonical pathway under oxidative-stress conditions. (A) STAT3 mitochondrial localization by immunofluorescence on LNCaP cells both untreated and treated with IL-6 and tBHP. Scale bar 20 µm. (B) Western blotting analysis of HIF-1α protein as a sensor of oxidative stress in LNCaP cells both untreated and treated with IL-6 and tBHP.

The p-S727 PTM drives the STAT3 non-canonical pathway under oxidative-stress conditions. (A) STAT3 mitochondrial localization by immunofluorescence on LNCaP cells both untreated and treated with IL-6 and tBHP. Scale bar 20 µm. (B) Western blotting analysis of HIF-1α protein as a sensor of oxidative stress in LNCaP cells both untreated and treated with IL-6 and tBHP.