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. 2019 Apr 12;20(8):1815. doi: 10.3390/ijms20081815

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Western blotting analysis of STAT3 PTMs on cellular extracts from DU-145 cells. (B) Real-time PCR analysis and relative expression of STAT3-target genes, representative of inflammation and oxidative stress in LNCaP cells and in DU-145 cells both untreated and treated for 8 h with 10 μM N-acetyl cysteine (NAC). Statistically significant differences (p < 0.05) between DU-145 cells both untreated and treated with NAC are marked by *, and values have been normalized to untreated LNCaP.