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. 2019 Apr 15;24(8):1476. doi: 10.3390/molecules24081476

Table 4.

Bioactivity of the ibuprofen and benzoylpropionic acid derivatives a.

Name GPCR Ion Channel Modulator Kinase Inhibitor Nuclear Receptor Ligand Protease Inhibitor Enzyme Inhibitor
Ibuprofen −0.17 −0.01 −0.72 0.05 −0.21 0.12
MBPA −0.35 −0.22 −0.82 −0.34 −0.53 0.00
DHBPA −0.19 −0.09 −0.68 −0.04 −0.43 0.20

a Score Values ≥0.00 = considerable biological activities; Score Values −0.50 to 0.00 = moderately active; score values ≤−0.50 = considerable inactive.