Table 3.
Principal risk factors for SUDEP (adapted from Reference [24]).
| Risk Factor | Weighted Log Odds Ratio (Adjusted Log OR ÷ Standard Error (SE)) |
Reference |
|---|---|---|
| >3 GTCS per year (versus 0 seizures) | 12.10 | Hesdorffer et al. [25] |
| >13 Seizures of any type in the past year (versus 0–2 seizures) | 4.20 | Nilsson et al. [26] |
| No AED * treatment (versus 1–2 AEDs) | 3.78 | Langan et al. [21] |
| 3 AEDs (versus 1) | 3.24 | Nilsson et al. [26] |
| ≥3 GTCS in past year (versus 0) | 3.04 | Walczak et al. [27] |
| 11–20 GTCS in the past 3 months (versus 0–5) | 2.39 | Langan et al. [21] |
| Age at onset of 0–15 years (versus >45 years) | 2.29 | Nilsson et al. [26] |
| IQ <70 | 2.23 | Walczak et al. [27] |
| 3–5 changes in AEDs per year (versus 0) | 2.16 | Nilsson et al. [26] |
| >3 AEDs in the last visit (versus 0–2) | 1.96 | Walczak et al. [27] |
* AED: antiepileptic drugs.