Figure 1.

Skin Microbiome Inhibits UV-B-Induced Suppression of Induction of CHS

(A) GF or control SPF mice were subjected to CHS assay as described in detail in Transparent Methods.

(B) The ear swelling differences between UV-B-irradiated and non-irradiated mice, with relatively reduced CHS response in GF compared with SPF (28.6% versus 59.5%), indicated immune protection by microbiome. Data shown represent mean ± SEM. N = 5 mice per experimental group; p value determined by Mann-Whitney test.

See also Figure S2.