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Representative PA images of U-87 MG and A431 xenografts acquired before and 24 hours after injection of ICG alone and ICG-RGD. In contrast to epidermoid carcinoma, the PA signal intensity in glioblastoma was significantly higher after ICG-RGD injection compared to measurements assessed at baseline and after free ICG administration (red region of interest) (adapted with permission from Capozza et al. [24], CC BY-NC-ND license, http://creativecommons.org/licenses/by-nc-nd/4.0/).
