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(a) Cannabinoid receptor 2 (CB2-R) mRNA levels in non-tumor adjacent mucosa and tumor tissue from colorectal cancer patients with and without metastases. Data are expressed as Fold induction. *** p < 0.005 (Student’s t-test). (b) Western blotting analysis of CB2-R protein in the same patients. Representative blots are also shown (No M = No Metastases; M = Metastases). * p < 0.05, *** p < 0.005 (ANOVA and Tukey’s multiple comparison test).
