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. 2019 Apr 18;20(8):1913. doi: 10.3390/ijms20081913

Table 1.

Baseline patient characteristics by drug use (n = 242).

Characteristics No. of Patients (%) p Value
PPI Use (n = 110) H2RA Use (n = 33) Non-Acid Suppressant Use (n = 99)
Age category (years)
<50 4 (3.63) 5 (15.15) 6 (6.06) 0.564
50–60 12 (10.91) 4 (12.13) 19 (19.19)
60–70 37 (33.64) 11 (33.33) 37 (37.37)
70–80 46 (41.82) 13 (39.39) 35 (35.35)
≥80 11 (10.00) 0 2 (2.02)
Sex
Female 49 (44.55) 20 (60.61) 44 (44.44) 0.202
Male 61 (55.45) 13 (39.39) 55 (55.56)
NSAID use 51 (46.36) 17 (51.52) 24 (24.24) <0.001
Sydney System Factor Score
Atrophy antrum 1.221 ± 0.778 1.160 ± 0.898 0.986 ± 0.778 0.254
corpus 0.755 ± 0.860 0.429 ± 0.898 0.613 ± 0.751 0.140
Metaplasia antrum 0.633 ± 0.889 0.515 ± 0.667 0.443 ± 0.667 0.411
corpus 0.284 ± 0.708 0.156 ± 0.448 0.122 ± 0.503 0.116
Mononuclear cell antrum 1.211 ± 0.639 1.303 ± 0.684 1.243 ± 0.648 0.713
corpus 1.211 ± 0.759 1.273 ± 0.674 1.102 ± 0.681 0.428
Neutrophil antrum 0.352 ± 0.646 0.455 ± 0.833 0.427 ± 0.778 0.925
corpus 0.444 ± 0.777 0.424 ± 0.708 0.433 ± 0.776 0.947
H. pylori antrum 0.389 ± 0.783 0.273 ± 0.626 0.333 ± 0.660 0.769
corpus 0.333 ± 0.641 0.424 ± 0.969 0.443 ± 0.841 0.826

Abbreviations: PPI, proton pump inhibitor; H2RA, histamine 2 receptor antagonist; NSAID, non-steroidal anti-inflammatory drug. Bold, statistical significance.