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. 2019 Apr 18;20(8):1913. doi: 10.3390/ijms20081913

Table 4.

Subgroup analysis of changes in the updated Sydney system score over time in relation to duration of H2RA use.

Sydney System Factor H2RA Long-term Use (n = 16) H2RA Short-term Use (n = 17) p Value
Score Coefficient (Point), Per Year (95% CI)
Atrophy antrum −0.037 (−0.117 to 0.044) 0.045 (−0.056 to 0.147) 0.382
corpus −0.034 (−0.067 to −0.001) 0.005 (−0.056 to 0.066) 0.108
Metaplasia antrum −0.053 (−0.100 to −0.0057) −0.022 (−0.075 to 0.031) 0.296
corpus −0.021 (−0.066 to 0.024) −0.008 (−0.035 to 0.019) 0.350
Mononuclear cell antrum −0.039 (−0.085 to 0.007) −0.078 (−0.135 to −0.022) 0.567
corpus −0.026 (−0.070 to 0.017) −0.051 (−0.102 to −0.001) 0.988
Neutrophil antrum −0.034 (−0.076 to 0.009) −0.066 (−0.129 to −0.002) 0.681
corpus −0.026 (−0.061 to 0.009) −0.063 (−0.124 to −0.003) 0.692
H. pylori antrum −0.023 (−0.057 to 0.010) −0.065 (−0.144 to 0.015) 0.443
corpus −0.035 (−0.084 to 0.014) −0.038 (−0.091 to 0.015) 0.633

Abbreviations: H2RA, histamine 2 receptor antagonist.