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Effects of compound 1 on oxygen consumption in the absence or in the presence of the inhibitor of phosphorylation FCCP. (A,B): RLM (1 mg/mL) were incubated in a medium containing succ (5 mM) and rot (1.25 µM). (C,D): RLM (1 mg/mL) were incubated in a medium containing glut (5 mM) and mal (1 mM). Test compound was added at indicated concentration. FCCP concentration was 0.1 μg/mg protein.
