Figure 6.
ClustalOmega sequence alignment of the proline-rich/polyproline region at the start of the CTD (just after the end of the coiled-coil in the helical domain). The alignment contains human merlin-ERM proteins and the insect ERM (Sfmoesin) from S. frugiperda. Prolines highlighted in red and other residues more commonly found in Type II poly-proline helices highlighted in orange. The alignment was carried out using Clustal Omega [80].