Table 1.
Sequence identity for multiple alignments between the human merlin-ERM paralogs dissected into domains. The Table entries give the percent sequence identity. In parentheses beneath each percentage, the number of identical residues is given divided by the length of the alignment, which was carried out using ClustalW [20].
| Merlin-ERM | ERM only | |
|---|---|---|
| Full-length | 37% (226/606) |
67% (394/586) |
|
FERM domain (Merlin: 1–312; ERM: 1–296) |
54% (169/313) |
81% (240/296) |
|
Helical domain (Merlin: 313–478; ERM: 297–469) |
23% (39/173) |
56% (99/173) |
|
C-terminal domain (including polyPro tract) (Merlin: 479–595; ERM: 470-C-terminus) |
15% (15/126) |
48% (57/118) |