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. 2019 Apr 25;24(8):1627. doi: 10.3390/molecules24081627

Figure 5.

Figure 5

Inflammatory mediator release in cinnamaldehyde-treated mouse skin wounds. The levels of (a) IL-6, (b) IL-17, (c) VEGF and (d) NO in skin wounds of animals infected or not with P. aeruginosa ATCC 27853. Cinnamaldehyde (0.5 mg/mL; 30 µL, n = 6) or 2% DMSO in sterile saline (30 µL, n = 6) were topically applied once a day for four days. The TRPA1 antagonist HC-030031 (30 mg/kg, i.p., n = 6) or vehicle (8% DMSO in saline, i.p., n = 6) were administered to animals receiving or not cinnamaldehyde. * p < 0.05, differs from vehicle-treated non-infected mice; # p < 0.05, differs from vehicle-treated P. aeruginosa infected mice; @ p < 0.05, differs from cinnamaldehyde-treated P. aeruginosa-infected mice. ND: not detected.