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. 2019 Apr 17;20(8):1897. doi: 10.3390/ijms20081897

Table 2.

Comparison between our model and prior studies.

Dataset References Size of Dataset SE SP ACC BACC
Training Present study 1254 (636+/618−) 0.818 0.748 0.783 0.783
[37] 1241 (683+/558−) 0.799 0.603 0.711 0.701
[30] 978 (571+/407−) 0.948 0.585 0.797 0.767
[33] 996 (541+/455−) 0.680 0.610 0.650 0.645
Test [37] 83 (66+/17−) 0.879 0.647 0.831 0.763
(0.909) (0.529) (0.831) (0.719)
[30] 85 (58+/27−) 0.707 0.815 0.741 0.761
(0.848) (0.345) (0.682) (0.597)
[33] 67 (28+/39−) 0.786 0.590 0.672 0.688
(0.536) (0.641) (0.597) (0.588)
Present study
(Entire external test set)
204 (125+/79−) 0.773 0.658 0.730 0.716
Present study
(Reverse validation)
312 (0+/312−) - - 0.689 -
(0.301)

In column of size of dataset, “+” and “−” denote the number of DILI-positives and DILI-negatives, respectively. For test, indicators within and outside parentheses were provided by prior studies and our model, respectively. We also investigated the performance of our model against the entire external test set which consisted of the external test sets provided by Ai et al., Zhang et al., and Kotsampasakou et al.