Table 1.
Description of publicly available studies used in the meta-analysis.
| Authors | Gene Expression Platforms | Validation Platforms | Muscle | Cancer Cachexia Study (Rodent Model or Cancer Type) |
Number of Samples (Cachectic/Control) |
Ref. |
|---|---|---|---|---|---|---|
| Mus Musculus | ||||||
| Tseng et al. 2015 | Illumina HiSeq 2500 | RT | Gastrocnemius | Colon-26 adenocarcinoma tumor-bearing mice | 3/3 | [36] |
| Roberts et al. 2013 | Illumina Genome Analyzer II | RT, WB | Quadriceps | Pancreatic adenocarcinoma-bearing mice | 2/2 | [37] |
| Bonetto et al. 2011 | Illumina MouseWG-6 v2.0 expression beadchip | RT, WB | Quadriceps | Colon-26 adenocarcinoma tumor-bearing mice | 4/4 | [38] |
| Gilabert et al. 2014 | Affymetrix Mouse Gene 1.0 ST Array | RT | Biceps femoris | Pancreatic adenocarcinoma-bearing mice | 3/3 | [39] |
| Shum et al. 2015 | Affymetrix Mouse Gene 1.0 ST Array | RT | Gastrocnemius | Colon-26 carcinoma tumor-bearing mice | 3/3 | [40] |
| Fontes-Oliveira et al. 2014 | Affymetrix RAE230Plus | RT | Extensor Digitorum Longus | Rats injected with AH-130 Yoshida ascites hepatoma cells | 7/6 | [41] |
| Homo Sapiens | ||||||
| Martinelli et al. 2016 | Agilent-014850 Whole Human Genome Microarray | RT, WB | Rectus abdominis | Pancreatic, colorectal, Hepatic, and renal cancers | 115 | [43] |
| Stephens et al. 2010 | Affymetrix GeneChip Human Genome U133 Plus 2.0 Array | RT | Rectus abdominis | Gastrointestinal cancer | 18/3 | [28] |
| Gallagher et al. 2012 | Affymetrix Human Genome U133 Plus 2.0 Array | RT | Quadriceps | Upper gastrointestinal cancer | 12/6 | [29] |
RT: quantitative reverse transcription polymerase chain reaction (RT-qPCR); WB: western blot; Ref: reference.