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. 2017 May 24;158(2):454–464. doi: 10.1093/toxsci/kfx108

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Published by Oxford University Press on behalf of the Society of Toxicology 2017. This work is written by US Government employees and is in the public domain in the US.

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Acrolein exposure induces hyperglycemia and glucose intolerance. A, GTT was conducted in Wistar and GK rats exposed to 0, 2, or 4 ppm acrolein for 1 day. B, AUC, normalized to the average Wistar 0 ppm, 0 min blood glucose levels, were calculated for each group. Data show mean ± SE (n = 6/group). ^‡p < .05 significantly different between strains at the same dose. ^‡p < .05 significantly different between strains at all doses. *p < .05 significantly different than 0 ppm group within same strain. ^§p < .05 significantly different than 2 ppm group within same strain. ^†p < .05 significantly different between strains at the same dose.