Table 2. Association of First-Line DMT Strategy and Change in EDSS Score at 5 Years: Adjusted Linear Regression Modela.
| Covariate | β Estimate (95% CI) | P Value |
|---|---|---|
| Unadjusted model | ||
| EIT treatment strategy | −0.92 (−1.45 to −0.41) | <.001 |
| Final adjusted model | ||
| EIT treatment strategy | −0.85 (−1.38 to −0.32) | .002 |
| Age at starting DMT | 0.03 (−0.002 to 0.05) | .03 |
Abbreviations: DMT, disease-modifying therapy; EDSS, Expanded Disability Status Scale; EIT, early intensive treatment.
a
First-line DMT strategy included EIT (n = 41) vs escalation approach (n = 138).