Table 3.
Evaluation of potential independent correlates of hrHPV E6/E7 mRNA-positivity among Ugandan women participating in a community-based study of cervical cancer screening. Separate analyses are shown for correlates of any hrHPV type and for a restricted set of HPV 16 or 18/45
| Characteristic | Any hrHPV Type Prevalence Ratio (95% CI) |
HPV 16 or 18/45 Prevalence Ratio (95% CI) |
||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted | P value | Adjusted | P value | Unadjusted | P value | Adjusted | P value | |
| Age, per additional yeara | 0.97 (0.96 to 0.99) | < 0.001 | 0.97 (0.96 to 0.99) | < 0.001 | 1.20 (0.92 to 1.58) | 0.18 | 0.96 (0.92 to 0.99) | 0.024 |
| Marital statusb | ||||||||
| Never married | Ref. | Ref. | Ref. | Ref. | ||||
| Married | 0.71 (0.45 to 1.13) | 0.15 | 0.87 (0.50 to 1.52) | 0.50 | 1.15 (0.28 to 4.55) | 0.84 | 1.19 (0.30 to 4.74) | 0.81 |
| Separated/divorced/widowed | 0.96 (0.59 to 1.57) | 0.17 | 1.02 (0.56 to 1.85) | 0.95 | 1.36 (0.32 to 5.81) | 0.68 | 1.30 (0.29 to 5.76) | 0.73 |
| Educational levelc | ||||||||
| None | Ref. | Ref. | Ref. | Ref. | ||||
| As least some primary | 1.28 (0.97 to 1.69) | 0.079 | 1.17 (0.86 to 1.58) | 0.32 | 0.94 (0.51 to 1.73) | 0.84 | 0.73 (0.38 to 1.38) | 0.33 |
| At least some secondary | 1.39 (1.01 to 1.91) | 0.041 | 1.12 (0.78 to 1.63) | 0.52 | 1.58 (0.82 to 3.08) | 0.17 | 0.99 (0.46 to 2.14) | 0.98 |
| At least some tertiary | 1.68 (0.77 to 3.69) | 0.19 | 1.36 (0.58 to 3.17) | 0.48 | 2.64 (0.64 to 10.4) | 0.17 | 1.69 (0.35 to 8.10) | 0.51 |
| Occupationd | ||||||||
| Unemployed | Ref: | Ref: | Ref. | Ref. | ||||
| Non-professional | 1.17 (0.89 to 1.56) | 0.26 | 1.08 (0.79 to 1.46) | 0.63 | 1.64 (0.90 to 2.99) | 0.11 | 1.35 (0.68 to 2.67) | 0.39 |
| Professional | 1.44 (1.12 to 1.84) | 0.004 | 1.33 (0.98 to 1.80) | 0.068 | 2.13 (1.25 to 3.63) | 0.005 | 1.56 (0.77 to 3.15) | 0.21 |
| Pregnancy statuse | ||||||||
| Not pregnant | Ref. | Ref. | Ref. | Ref. | ||||
| Pregnant | 1.31 (1.02 to 1.69) | 0.036 | 1.37 (1.04 to 1.80) | 0.026 | 1.14 (0.60 to 2.17) | 0.69 | 1.30 (0.67 to 2.52) | 0.43 |
| HIV infection statusf | ||||||||
| HIV-uninfected | Ref. | Ref. | Ref. | Ref. | ||||
| HIV-infected | 2.07 (1.67 to 2.57) | < 0.001 | 2.20 (1.74 to 2.78) | < 0.001 | 2.62 (1.57 to 4.38) | < 0.001 | 3.08 (1.77 to 5.35) | < 0.001 |
aAge was adjusted for education, HIV infection status, marital status, pregnancy, and occupation
bMarital status was adjusted for age, education, HIV infection status, pregnancy, and occupation
cEducation was adjusted for age, HIV infection status, marital status, pregnancy, and occupation
dOccupation was adjusted for age, education, HIV infection status, marital status, and pregnancy
ePregnancy was adjusted for age, education, HIV infection status, marital status and occupation
fHIV infection status was adjusted for age, education, marital status, pregnancy, and occupation