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. 2019 May 13;17:64. doi: 10.1186/s12951-019-0498-7

Fig. 1.

Fig. 1

Schematic illustration of the design and evaluation of PAMAM G3.0-coated compound liposomes. a Synthesis process of PAMAM coated compound liposomes. Loading BBH and CHR into the different chamber of liposomes by thin film and active load, respectively, and PAMAM G3.0 was loaded into the surface of compound liposomes via electrostatic interaction. b Comprehensive evaluation of PAMAM coated compound liposomes including characterization, in vitro, in vivo transport efficiency, preliminary pharmacodynamics studies and opthalmic irritation studies