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. 2019 May 14;19:149. doi: 10.1186/s12887-019-1516-5

Table 4.

Regression Results For Maternal Alcohol Use and Infant Gross Motor Outcomes (Pooled Data, N = 1324)

Unadjusted b (95%CI) Adjusted for maternala b (95%CI) Adjusted for maternalb b (95%CI) Adjusted for maternalc b (95%CI) Adjusted for maternal + infantd b (95%CI)
Trimester 1a (first 6 weeks) (n = 1324)
 Abstinent Ref Ref Ref Ref Ref
 Low (≤7 drinks per week, up to 2 per occasion) −0.29 (−0.68–0.11) −0.35 (−0.75–0.05) −0.35 (−0.74–0.05) −0.37 (−0.78–0.03) −0.39 (−0.79–0.01)
 Moderate (≤7 drinks per week, > 2 to ≤4 per occasion) − 0.49 (−1.24–0.27) − 0.64 (−1.39–0.12) − 0.63 (−1.39–0.12) − 0.62 (−1.38–0.14) − 0.66 (−1.42–0.1)
 Binge (≤7 drinks per week, > 4 per occasion) − 0.23 (− 0.66–0.19) −0.32 (− 0.75–0.12) −0.31 (− 0.75–0.13) −0.29 (− 0.74–0.15) −0.3 (− 0.74–0.15)
 Heavy (> 7 drinks per week, weekly or more) 0.02 (− 0.44–0.48) − 0.04 (− 0.5–0.42) − 0.02 (− 0.5–0.45) −0.02 (− 0.5–0.46) −0.06 (− 0.54–0.42)
Trimester 1b* (second 6 weeks) (n = 1227)
 Abstinent Ref Ref Ref Ref Ref
 Low (≤7 drinks per week, up to 2 per occasion) −0.23 (− 0.63–0.17) −0.31 (− 0.71–0.09) −0.3 (− 0.71–0.1) −0.31 (− 0.72–0.1) −0.32 (− 0.73–0.09)
 Trimester 2* (n = 1259)
 Abstinent Ref Ref Ref Ref Ref
 Low (≤7 drinks per week, up to 2 per occasion) −0.02 (− 0.35–0.32) 0.03 (− 0.32–0.37) 0.03 (− 0.32–0.38) 0.02 (− 0.33–0.37) − 0.01 (− 0.36–0.34)
Trimester 3* (n = 1270)
 Abstinent Ref Ref Ref Ref Ref
 Low (≤7 drinks per week, up to 2 per occasion) −0.12 (− 0.46–0.21) −0.03 (− 0.37–0.31) −0.03 (− 0.38–0.31) −0.04 (− 0.4–0.31) −0.08 (− 0.43–0.28)

Note: Standard drink = 10 g of alcohol. *Moderate, Binge and Heavy categories were not assessed after T1a due to infrequent reporting of these drinking patterns in the sample

aAdjusted for Mother-related background variables (Age at birth, Education, SEIFA, State of residence, Country of birth, Single parent household, Aboriginal and Torres Strait Islander status, Native language)

bAdjusted for Mother-related background variables + Substance use variables (Pregnancy smoked, Pregnancy illicit drugs)

cAdjusted for Mother-related background variables + Physical and psychological variables (Pregnancy Anxiety, IQ, Parity, BMI)

dAdjusted for all previous Mother-related variables + Infant-related variables (Gestational age)