Table 3.
Multivariate analyses of prognostic factors for cancer disease-free survival in the FUSCC
| Variables | Cox proportional hazards | ||
|---|---|---|---|
| Hazard ratio | 95% CI | p value | |
| Adjuvant chemotherapy | 0.855 | ||
| No | 1 (reference) | ||
| Yes | 0.912 | 0.342–2.432 | |
| Gender | 0.215 | ||
| Female | 1 (reference) | ||
| Male | 1.340 | 0.844–2.127 | |
| Age | 1.016 | 0.972–1.061 | 0.481 |
| Clinical T stage | 0.446 | ||
| T2 | 1 (reference) | ||
| T3/4 | 0.697 | 0.275–1.766 | |
| Clinical N sage | 0.401 | ||
| N0 | 1 (reference) | ||
| N1–2 | 0.657 | 0.247–1.751 | |
| CRM | 0.707 | ||
| Negative | 1 (reference) | ||
| Positive | 1.194 | 0.474–3.010 | |
| EMVI | 0.222 | ||
| Negative | 1 (reference) | ||
| Positive | 0. 462 | 0.134–1.597 | |
| Operation | 0.391 | ||
| AR | 1 (reference) | ||
| APR | 1.503 | 0.593–3.809 | |
| Lymph node examined | 0.381 | ||
| ≤ 12 | 1 (reference) | ||
| > 12 | 0.406 | 0.054–3.049 | |
CRM, circumferential resection margin; EMVI, extramural venous invasion; AR, anterior resection; APR, abdominoperineal resection