Fig. 3.

The predictive performance of the RISK score signature in different validation cohorts. Interaction analysis between treatments (with versus without TMZ) and risk subgroups (low-risk versus high-risk) in a TCGA-Brennan et al. and b GSE60274. Only patients with standard RT regimen were included for analysis in order to reduce potential bias by heterogeneous treatment regimen. RT radiotherapy, TMZ temozolomide