. 2019 Mar 30;113(5):287–290. doi: 10.1093/trstmh/trz014

Table 1.

Research and development (R&D) funding and associated DALYs in 2017 for RHD and 15 major tropical infectious diseases (Global Burden of Disease Study 2017, G-FINDER public research tool 2017) with associated DNI

Disease^a	Yearly R&D spending (million US$)^b						DALYs^d (1000s)	R&D (US$ per DALY)	DNI^e
Disease^a	2013	2014	2015	2016	2017	5-y average^c	DALYs^d (1000s)	R&D (US$ per DALY)	DNI^e
RHD	0.9	1.3	2.3	1.3	1.2	1.39	9393	0.15	3.83
Cysticercosis	1.79	2.39	2.69	3.61	5.37	3.17	1608	1.97	2.71
Soil-transmitted helminths	8	7.7	8.3	7	6.3	7.47	1919	3.89	2.41
Typhoid and paratyphoid fever	47.8	47.9	55	71.4	63.7	57.17	9801	5.83	2.23
Trachoma	2.2	1.35	1.15	2.18	2.67	1.91	302.9	6.31	2.2
Meningococcal meningitis	18.9	12.23	7.44	24.57	10.67	14.76	2279	6.48	2.19
Onchocerciasis	14.8	9.7	12.7	10.2	12	11.89	1343	8.85	2.05
Lymphatic filariasis	15.38	21.36	13.71	15.82	15.21	16.29	1364	11.94	1.92
Malaria	532.6	578.1	564.5	576.8	624	575.18	45 015	12.78	1.89
TB	564.4	569.4	577.9	570.4	615.4	579.48	44 997	12.88	1.89
Schistosomiasis	24.51	26.4	20.36	18.37	24.24	22.77	1431	15.91	1.8
HIV/AIDS	1119.99	1080.93	1030.85	1102.3	1256.76	1116.16	54 446	20.5	1.69
Pneumococcal meningitis	69.2	51.38	73.67	66.1	63.35	64.74	3077	21.04	1.68
Dengue	76	85.86	101.13	112.8	81.33	91.44	2923	31.28	1.5
Leishmaniasis	34.27	44.67	40.12	41.25	44.15	40.89	774	52.83	1.28
Chagas disease	27.2	21.37	19.11	24.55	17.73	21.99	232	94.78	1.02
Total	2558	2562	2531	2649	2844	2627	180 905	–	–

^aAll diseases for which paired disease-specific data were available from G-FINDER and the Global Burden of Disease Study 2017.

^bTotal grants to disease projects in 2017 (G-FINDER).

^cMean of funding years 2013–2017, adjusted for inflation to 2017 US dollars.

^dDALYs (Global Burden of Disease Study 2017).

^eCalculated as the negative common logarithm of (DALYs [in thousands]/Funding [in US$ millions]).