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. Author manuscript; available in PMC: 2019 Aug 15.
Published in final edited form as: Am J Cardiol. 2018 Jun 20;122(4):554–559. doi: 10.1016/j.amjcard.2018.04.060

Table 2.

Sodium nitrite safety outcomes and early hospital outcomes

Characteristic Low dose
(n=59)
High dose
(n=61)
P
Any ROSC 28 (48%) 30 (49%) 0.85
Norepinephrine after study 7 (12%) 7 (12%) 0.97
Re-arrest in field (all) 9 (15%) 15 (25%) 0.20
Re-arrest in field (ROSC) 9 (32%) 15 (50%) 0.17
First systolic blood pressure 124±32 (n=22) 125±38 (n=22) 0.93
First systolic blood pressure in hospital 116±33 (n=23) 112±41 (n=19) 0.75
Transported to hospital 34 (58%) 32 (52%) 0.57
pH first arterial blood gas 7.1±0.2 (n=30) 7.1±0.2 (n=28) 0.63
Pressors in first 24 hours 22/34 (65%) 22/31 (71%) 0.59
Hospital cooling 17/34 (50%) 13/31 (42%) 0.34
First hospital temperature 34.1±3.2 (n=30) 35.2±1.8 (n=24) 0.07
Withdrawal of support 13/34 (38%) 6/29 (32%) 0.13
Re-arrest first 2 hours of hospitalization 4/26 (15%) 8/27 (30%) 0.22
ICU days 7.3±8.3 (n=19) 3.2±4.2 (n=16) 0.15
Positive troponin 28 (48%) 26 (43%) 0.60
Cardiac cath 15/34 (44%) 10/31(32%) 0.33
Percutaneous coronary intervention 4/34 (12%) 2/31 (6%) 0.46
Neurologic status 0.54
 CPC 1 or 2 11 (19%) 7 (12%)
 CPC 3 o4 3 (5%) 3 (5%)
 Dead, other 45 (76%) 51 (84%)
Survival to discharge 14 (24%) 10 (16%) 0.32