Table 4.
Patients and VOD characteristics
| Patients | |||||
|---|---|---|---|---|---|
| Parameter | #1 | #2 | #3 | #4 | #5 |
| Age, (years) | 26 | 31 | 39 | 46 | 50 |
| Prior ASCT | No | Yes | No | Yes | No |
| Conditioning | NA | Flu/Clo | NA | Bu/Flu/Clo | NA |
| # cycles | 5 | 3 | 2 | 3 | 3 |
| Subsequent ASCT | Yes | No | Yes | No | Yes |
| Conditioning | Bu/Clo | NA | Bu/Flu/Clo/SAHA | NA | Bu/Flu post transplant Cy |
| Dose | 1.3/1/1/1 | 1.8/1.3/1.3 | 1.8/1.3 | 1.3/1/1 | 1.3/1/1 |
| Status | Died | Died | Died | Died | Died |
VOD=veno-occlusive disease; ASCT=allogeneic stem cell transplantation; Y=yes; N=no; Flu=fludarabine; Clo=clofarabine; Cy=cyclophosphamide; Bu=busulfan; SAHA = suberoylanilide hydroxamine; NA=not applicable