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. 2019 May 7;10:496. doi: 10.3389/fphar.2019.00496

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Copyright © 2019 Qin, Zhang, Yang, Li, Xu, Yao, Zhang, Gonzalez and Yao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The protein expression (A) and efficiency of the knockdown (B) of BCRP, MRP1, MRP3, and MRP4 in HeLa1A9 cells after stable transfection of BCRP-shRNA, MRP1-shRNA, MRP3-shRNA, and MRP4-shRNA into HeLa1A9 cells, respectively. All the experiments were conducted in triplicate. ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001 relative to the parameters of the control cells (scrambled shRNA transfection).