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. Author manuscript; available in PMC: 2019 May 14.
Published in final edited form as: Anal Chem. 2019 Feb 6;91(4):3110–3117. doi: 10.1021/acs.analchem.8b05709

Figure 3.

Figure 3.

Generalized synthetic strategies that allow for the direct preparation of fluorescent rosol dyes. A) Conventional synthetic strategy that affords only non-NIR (3’-amino-substituted) fluorescent rosol dyes of limited diversity. B) Newly-established synthetic strategy that affords non-NIR and NIR (2’,3’-diamino-substituted) fluorescent rosol dyes of broad diversity.