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. 2019 Mar 18;18(3):e12936. doi: 10.1111/acel.12936

Figure 4.

Figure 4

Collagen disruption prevents stiffness in aortas of LmnaG609G/G609G mice. Diameter–tension relationships and corresponding linear regression slopes in aortic rings from Lmna+/+mice (n = 5–10) and LmnaG609G/G609G mice (n = 5–10) after incubation with drugs affecting vessel structure: collagenase (collagen degradation), elastase (elastin–fiber degradation), and mycalolide B (depolymerization of F‐actin to G‐actin). Vehicle was used as control