Table II.
ADC | % of ADC | % HPV positive | |
Usual type | 75 | 80 - 100 | |
Intestinal | 8 | 83 - 100 | |
Villoglandular* | 3-6 | 100 | |
Signet ring cell | rare | 100 | |
Endometrioid** | rare | 100 | |
- From SCJ | 100 | ||
- From upper cervix/lower uterine | 0 | ||
Serous | very rare | 30 | |
Clear cell | 2-7 | 28 | |
Gastric type | unknown | 0 | |
Mesonephric | rare | 0 |
*villogladular ADC is a well differentiated variant of endocervical, endometrioid, or intestinal ADC.
** Endometrioid ADC is a rare variant developing from either tuboendometrioid metaplasia or endometriosis. The can be divided in tumors originating from the squamous columnar junction zone or from the upper part of the endocervix and lower uterine segment.