Table 1.

Comparison of hormone levels between diabetic addicted (case) and diabetic non-addicted (control) male and female rats. Data from seven animals in each group

Hormones	Groups
	Male, (mean ± SEM)			Female, (mean ± SEM)
	Diabetic Addicted (Case)	Diabetic non-Addicted (Control)	P-Value	Diabetic Addicted (Case)	Diabetic non-Addicted (Control)	P-Value
T3 (ng/dL)	1.171±0.058	0.832±0.047	0.001*	1.452±0.173	1.358±0.034	0.612
T4 (μg/dL)	29.4±2.96	29.771±1.854	0.917	35.114±2.084	40.714±5.922	0.4
17OH-Progesterone (ng/mL)	0.2±0.025	0.257±0.037	0.234	0.968±0.230	3.984±0.846	0.011*
Testosterone (ng/mL)	0.3±0.095	0.394±0.089	0.524	0.395±0.077	0.218±0.078	0.134
DHEA-S (ng/mL)	0.557±0.183	0.085±0.025	0.042*	0.072±0.016	0.245±0.064	0.023

Mean serum level of T3 was significantly increased in male diabetic addicted rats compared to male diabetic non-addicted rats (P=0.001). The mean level of 17-hydroxyprogesterone was decreased in male and female diabetic addicted rats as compared to diabetic non-addicted group, which was significant in females (P=0.011). The mean level of DHEA-S in male diabetic addicted rats had a significant increase in comparison with the diabetic non-addicted group (P=0.042), while, a significant decrease was observed in female rats (P=0.023). *Significance at 0.05 levels.