Table 3.

Comparison of hormone levels between non-diabetic addicted (case) and non-diabetic Non-addicted (control) male and female rats. Data from seven animals in each group

Hormones	Groups
	Male, (mean ± SEM)			Female, (mean ± SEM)
	Non-diabetic Addicted (Case)	Non-diabetic Non-addicted (Control)	P-Value	Non-diabetic Addicted (Case)	Non-diabetic Non-addicted (Control)	P-Value
T3 (ng/dL)	1.337±0.111	0.872±0.044	0.002*	1.561±0.132	1.334±0.041	0.128
T4 (μg/dL)	29.191±2.928	29.557±1.834	0.917	34.220±2.432	32.714±6.625	0.835
17OH-Progesterone (ng/mL)	0.217±0.022	0.251±0.034	0.421	0.734±0.072	1.417±0.091	< 0.001*
Testosterone (ng/mL)	0.261±0.034	0.351±0.037	0.104	0.617±0.041	0.242±0.029	< 0.001*
DHEA-S (ng/mL)	0. 480±0.081	0.107±0.034	0.001*	0.224±0.077	0.248±0.044	0.790

The Table 3 illustrates that in male non-diabetic addicted rats, the mean level of T3 had a significant increase in comparison with control group (P=0.002). However, the mean level of DHEA-S showed a significant decrease in non-diabetic addicted compared to non-diabetic non-addicted (P=0.001). Comparison of female non-diabetic non-addicted with non-diabetic addicted group, the mean levels of 17-hydroxyprogesterone and testosterone were significantly decreased and increased, respectively (P<0.001 for both comparisons). *Significance at 0.05 levels.